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. 2019 Mar 1;23(5):3271–3279. doi: 10.1111/jcmm.14213

Figure 2.

Figure 2

Knockdown of lncRNA‐ZEB2‐AS1 suppressed the proliferation and invasion of MDA231 cells. A, Depletion of lncRNA‐ZEB2‐AS1 in MDA231 cells by lncRNA‐ZEB1‐AS1‐RNAi. B, Cells proliferation activity was detected via CCK‐8 assays. C, Left: Colony formation assay results showed that the depletion of lncRNA ZEB2‐AS1 led to the remarkable decrease of MDA231/si‐ZEB2‐AS1 content. Right: Quantification of colony numbers. D, Left: Invasion of MDA231 cells analyzed with transwell chambers (scale bars = 100 μm). Right: Quantification of penetrating cells. E, Left: Wound healing assay (scale bars = 200 μm). Right: Migration distance (*, P < 0.05).