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. 2019 Feb 7;23(5):3257–3270. doi: 10.1111/jcmm.14212

Table 3.

Down‐regulation of miR‐205 and up‐regulation of AR expression decrease the MAP, ICP and ICP/MAP value

Group Number MAP (mm Hg) ICP (mm Hg) ICP/MAP
Normal 10 112.93 ± 10.28 98.45 ± 9.82 0.88 ± 0.12
DMED 10 89.32 ± 7.45a 27.46 ± 3.41a 0.31 ± 0.06a
NC 10 91.62 ± 8.69a 26.75 ± 2.61a 0.3 ± 0.03a
miR‐205 mimic 10 89.57 ± 7.26a, b 19.68 ± 0.83a, b 0.22 ± 0.02a, b
miR‐205 inhibitor 10 129.49 ± 9.65a, b 62.34 ± 5.66a, b 0.49 ± 0.07a, b
AR overexpression 10 132.81 ± 10.73a, b 61.62 ± 6.52a, b 0.46 ± 0.03a, b
miR‐205 mimic +AR overexpression 10 87.46 ± 8.28a 26.98 ± 2.46a 0.31 ± 0.04a

AR, androgen receptor; DMED, erectile dysfunction rats with diabetic mellitus; miR‐205, microRNA‐205; NC, negative control.

The level of MAP, ICP and ICP/MAP were measurement data, which was expressed as mean ± SD; data in each group was analysed with ANOVA; the sample size of each group was 10; the experiment was repeated for three times.

a

P < 0.05 vs. the normal group.

b

< 0.05 vs. the DMED group and the NC group.