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Raddeanin A (RA) inhibits the transcription of the AR gene. A and B, qRT‐PCR analysis showing RA, at 3 μmol/L, decreases AR‐FL and AR‐V mRNA levels in a time‐dependent manner in the presence or absence of 1 nmol/L R1881. C, Luciferase assay showing RA inhibition of the activity of a 1.7 kb proximal AR promoter. Cells transfected with the pGL4‐ARpro1.7 construct were treated with 3 μmol/L RA for 12 h. *P < 0.05 from the control group
