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. 2019 Apr 26;2019(4):CD004055. doi: 10.1002/14651858.CD004055.pub2
Medical term Explanation
Acrovesicular eczema Form of vesicular hand eczema. (Large) vesicle eruptions on the palms that usually tend to recur. Also called dyshidrotic eczema or pompholyx
Betamethasone Topical corticosteroid, high potency
Clobetasol propionate Topical corticosteroid, very high potency
Desonide Topical corticosteroid, low potency
Dyshidrotic hand eczema Form of vesicular hand eczema. (Large) vesicle eruptions on the palms that usually tend to recur. Also called dyshidrotic eczema, pompholyx or acro vesicular eczema
Fluprednidene acetate Topical corticosteroid, medium potency
Heterogeneity Differences in which studies have been undertaken with regard to methods and/or materials
Hydrocortisone butyrate Topical corticosteroid, low potency
Hyperkeratotic hand eczema Form of hand eczema with areas of thick scaling on the palms, also called tylotic hand eczema
IGA Investigator global assessment: global assessment of disease severity usually on a 5‐point scale
Immunomodulator Drug which changes the immune response such as tacrolimus
Immunosuppressor Drug which suppresses the immune response such ad topical corticosteroids
Iontophoresis Treatment by which the skin is soaked in (tap) water through which a weak electric current is passed
Mometasone furoate cream Potent steroid cream
NB‐UVB Narrow‐band ultraviolet B
Nummular hand eczema Round ("coin sized") eczematous patches on the back of the hands
Palmar Hand palms, the inside surface of the hands
Palmoplantar Hand palms and foot soles
Phase I clinical trial A clinical trial of a new drug or therapy. Phase I trials are conducted in small groups of participants
Phase II clinical trial A clinical trial of a new drug or therapy. Phase II trials are conducted in larger groups of participants than phase I trials
Pimecrolimus Topical calcineurin inhibitor, also known as "elidel"
Placebo Simulated or otherwise medically ineffective treatment
Pompholyx Form of vesicular hand eczema. (Large) vesicle eruptions on the palms that usually tend to recur. Also called dyshidrotic eczema, pompholyx or acro vesicular eczema
Potency Strength
Prevalence The proportion of a population having a particular condition or characteristic: e.g. the percentage of people in a city with hand eczema, or the proportion of people who smoke
Primary care Health care provided at the principal point of consultation for patients within a healthcare system, e.g. GP
Pruritus Itch
Psychosomatic disorder A disorder in which physical symptoms originate from mental or emotional causes
Pulpitis A dry, fissured, scaling dermatitis of the fingertips with occasional episodes of vesicles. Also known as fingertip dermatitis
PUVA (Topical and oral) psoralen combined with UVA
Randomised control trials A study in which a number of similar people are randomly assigned to two (or more) groups to test a specific drug, treatment or other intervention. (National Institute for Health and Care Excellence)
RR Relative risk
Secondary care Health care provided by medical specialists and other health professionals, including dermatologists, who generally do not have first contact with patients. This contains hospital and out‐patient care
Systemic treatment Treatment which does not pertain to a certain surface area but might affect the entire body, usually taken by mouth or injection.
Tacrolimus Topical calcineurin inhibitor, also known as "protopic"
Teratogenicity Developmental abnormalities in the foetus
Therapy A treatment that helps someone feel better, grow stronger, etc., especially after an illness (Cambridge dictionary)
Topical treatment Treatment pertaining to a certain surface area (usually the skin) and only affecting the area to which it is applied
Transepidermal water loss (TEWL) The amount of water that moves from inside the body to the surrounding atmosphere through the epidermal layer of the skin by means of diffusion and evaporation.
Tylotic hand eczema Form of hand eczema with areas of thick scaling on the palms, also called hyperkeratotic hand eczema
UVA‐1 Form of UV‐phototherapy which only uses the longer UV wavelengths (340 to 400 nm) and reduces the risk of burning, which is associated with the shorter‐wavelength UVA2 (320 to 340 nm) and UVB (290 to 320 nm).
UVB Ultraviolet B
VAS (Visual Analogue Scale) Continious scale to measure a (subjective) response
Vehicle Something used to transport people or goods (Cambridge dictionary), in this case something to help the treatment get transport in/on the skin, but a vehicle alone (without the active substance) can be used as placebo.