Medical term |
Explanation |
Acrovesicular eczema |
Form of vesicular hand eczema. (Large) vesicle eruptions on the palms that usually tend to recur. Also called dyshidrotic eczema or pompholyx |
Betamethasone |
Topical corticosteroid, high potency |
Clobetasol propionate |
Topical corticosteroid, very high potency |
Desonide |
Topical corticosteroid, low potency |
Dyshidrotic hand eczema |
Form of vesicular hand eczema. (Large) vesicle eruptions on the palms that usually tend to recur. Also called dyshidrotic eczema, pompholyx or acro vesicular eczema |
Fluprednidene acetate |
Topical corticosteroid, medium potency |
Heterogeneity |
Differences in which studies have been undertaken with regard to methods and/or materials |
Hydrocortisone butyrate |
Topical corticosteroid, low potency |
Hyperkeratotic hand eczema |
Form of hand eczema with areas of thick scaling on the palms, also called tylotic hand eczema |
IGA |
Investigator global assessment: global assessment of disease severity usually on a 5‐point scale |
Immunomodulator |
Drug which changes the immune response such as tacrolimus |
Immunosuppressor |
Drug which suppresses the immune response such ad topical corticosteroids |
Iontophoresis |
Treatment by which the skin is soaked in (tap) water through which a weak electric current is passed |
Mometasone furoate cream |
Potent steroid cream |
NB‐UVB |
Narrow‐band ultraviolet B |
Nummular hand eczema |
Round ("coin sized") eczematous patches on the back of the hands |
Palmar |
Hand palms, the inside surface of the hands |
Palmoplantar |
Hand palms and foot soles |
Phase I clinical trial |
A clinical trial of a new drug or therapy. Phase I trials are conducted in small groups of participants |
Phase II clinical trial |
A clinical trial of a new drug or therapy. Phase II trials are conducted in larger groups of participants than phase I trials |
Pimecrolimus |
Topical calcineurin inhibitor, also known as "elidel" |
Placebo |
Simulated or otherwise medically ineffective treatment |
Pompholyx |
Form of vesicular hand eczema. (Large) vesicle eruptions on the palms that usually tend to recur. Also called dyshidrotic eczema, pompholyx or acro vesicular eczema |
Potency |
Strength |
Prevalence |
The proportion of a population having a particular condition or characteristic: e.g. the percentage of people in a city with hand eczema, or the proportion of people who smoke |
Primary care |
Health care provided at the principal point of consultation for patients within a healthcare system, e.g. GP |
Pruritus |
Itch |
Psychosomatic disorder |
A disorder in which physical symptoms originate from mental or emotional causes |
Pulpitis |
A dry, fissured, scaling dermatitis of the fingertips with occasional episodes of vesicles. Also known as fingertip dermatitis |
PUVA |
(Topical and oral) psoralen combined with UVA |
Randomised control trials |
A study in which a number of similar people are randomly assigned to two (or more) groups to test a specific drug, treatment or other intervention. (National Institute for Health and Care Excellence) |
RR |
Relative risk |
Secondary care |
Health care provided by medical specialists and other health professionals, including dermatologists, who generally do not have first contact with patients. This contains hospital and out‐patient care |
Systemic treatment |
Treatment which does not pertain to a certain surface area but might affect the entire body, usually taken by mouth or injection. |
Tacrolimus |
Topical calcineurin inhibitor, also known as "protopic" |
Teratogenicity |
Developmental abnormalities in the foetus |
Therapy |
A treatment that helps someone feel better, grow stronger, etc., especially after an illness (Cambridge dictionary) |
Topical treatment |
Treatment pertaining to a certain surface area (usually the skin) and only affecting the area to which it is applied |
Transepidermal water loss (TEWL) |
The amount of water that moves from inside the body to the surrounding atmosphere through the epidermal layer of the skin by means of diffusion and evaporation. |
Tylotic hand eczema |
Form of hand eczema with areas of thick scaling on the palms, also called hyperkeratotic hand eczema |
UVA‐1 |
Form of UV‐phototherapy which only uses the longer UV wavelengths (340 to 400 nm) and reduces the risk of burning, which is associated with the shorter‐wavelength UVA2 (320 to 340 nm) and UVB (290 to 320 nm). |
UVB |
Ultraviolet B |
VAS (Visual Analogue Scale) |
Continious scale to measure a (subjective) response |
Vehicle |
Something used to transport people or goods (Cambridge dictionary), in this case something to help the treatment get transport in/on the skin, but a vehicle alone (without the active substance) can be used as placebo. |