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. 2019 Apr 26;2019(4):CD004055. doi: 10.1002/14651858.CD004055.pub2

Said 2010.

Methods Parallel‐group, randomised controlled trial
This study was carried out in a secondary care setting in a single dermatology department in Singapore
Participants 47 participants with chronic vesicular hand eczema
Dropouts: 7
Inclusion criteria of the trial
  • Chronic vesicular hand eczema


Exclusion criteria of the trial
  • Not defined


Study population
  • Gender: not stated

  • Age: not stated

Interventions Interventions
• UVA‐1 phototherapy 3 times a week for 6 weeks in 24 participants
• Betamethasone‐valerate 0.1% cream twice a day for 6 weeks in 23 participants
Duration
6 weeks active treatment, 6 weeks follow‐up. Total duration: 12 weeks
Outcomes Primary outcomes of the trial
Not defined
Other outcomes
  • Degree of improvement based on the Dyshidrotic Area and Severity Index (DASI) at week 3, week 6, and week 12

  • Adverse events

Notes Conference abstract, from which only limited information can be extracted
We were unable to contact the study authors
Declarations of interest: not stated
Funding: not stated
Sample size rationale: not stated
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "twenty‐four patients were randomly assigned to..."
Comment: insufficient data
Allocation concealment (selection bias) Unclear risk Insufficient data
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Quote: "open‐label study"
Comment: no blinding
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Quote: "open‐label study"
Comment: no blinding
Incomplete outcome data (attrition bias) 
 All outcomes Low risk More than 80% of participants were analysed (40/47)
Selective reporting (reporting bias) Unclear risk No trial register was found
Other bias Unclear risk Baseline comparisons: no baseline comparisons regarding group differences (randomisation check)
Diagnostic certainty: no
The study was completed