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. 2019 Apr 26;2019(4):CD004055. doi: 10.1002/14651858.CD004055.pub2

Beitner 1996.

Methods Randomised controlled trial
This study was conducted at a single centre in Sweden
The study probably was not blinded
Participants 30 consecutive participants with different dermatological hand dermatoses including pustulosis palmoplantaris (n = 5), psoriasis (n = 1), tylotic eczema (n = 4), atopic eczema (n = 3), dyshidrotic eczema (n = 1), allergic eczema (n = 7), and non‐allergic eczema (n = 1), both allergic eczema and dyshidrotic (n = 2)
Dropouts: 6
Inclusion and exclusion criteria were not stated
Interventions Intervention
• Clobetsaol propionate (Dermovate Glaxo) solution under occlusion with a hydrocolloid dressing twice a week for the first 2 weeks and once a week for the next 2 weeks
• Clobetasol propionate ointment under occlusion with a hydrocolloid dressing twice a week for the first 2 weeks and once a week for the next 2 weeks
Follow‐up included a visit 12 weeks after the start of treatment
Outcomes Primary outcomes of the trial
Not stated
Other outcomes
  • Symptom severity for itching, erythema, infiltration, and scaling, each graded on a 4‐point scale (0 = no symptoms, 1 = mild, 2 = moderate, 3 = severe)

  • Participant‐rated severity of itch on a visual analogue scale (VAS)

  • Vesicles/pustules: absent or present

  • Relapse within 12 weeks

  • Adverse events

Notes Study results for hand eczema participants were not presented separately, and we were unable to obtain additional data from the study author
This study was published as a very concise letter to the editor, and a lot was uncertain, for example, visits and outcome parameters