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. 2019 Apr 26;2019(4):CD004055. doi: 10.1002/14651858.CD004055.pub2

Lassus 1981.

Methods Randomised within‐participant study
Probably conducted at a single centre in Finland
This study claims to be double‐blind
Participants 80 patients with various symmetrical eczemas: allergic eczema (n = 27), atopic dermatitis (n = 21), toxic hand eczema (n = 10), chronic eczema (n = 7), stasis eczema (n = 5), nummular eczema (n = 4), neurodermatitis (n = 3), dyshidrotic eczema (n = 2), seborrhoeic eczema (n = 1) and 40 participants with psoriasis
Dropouts: probably none
Inclusion and exclusion criteria were not stated
Interventions All participants were first treated with placebo for 1 week. Afterwards, they were randomised
Intervention
• Budesonide 0.025% ointment twice daily probably with occlusive dressing
• Betamethasone‐17‐valerate 0.1% ointment twice daily probably with occlusive dressing
Duration is not really clear from the article, but probably 2 weeks
Outcomes Primary outcomes of the trial
Not defined
Other outcomes
  • Investigator‐rated severity for itching, scaling, erythema, and induration from 0 to 4 (0 = absent, 4 = very severe) at baseline, week 1, and week 2

  • Investigator‐rated overall expression of response at baseline, week 1, and week 2

  • Participant‐rated overall expression of response at baseline, week 1, and week 2

  • Adverse events

Notes RCT on different forms of symmetrical eczema; this study is published alongside a study on psoriasis. We were unable to reconstruct the results in participants with hand eczema, and we were unsuccessful in locating study authors