NCT00843466.

Methods	Randomised open‐label parallel‐group study
Participants	46 patients who experience mild to moderate hand dermatitis induced by frequent cleansing Inclusion criteria 18 to 65 years of age General good health Hands free of cuts and abrasions Agrees to adhere to the requirements listed in the informed consent Willing and able to use a mild, moisturising, non‐antibacterial cleanser for all handwashing purposes for the duration of the test period Willing to refrain from participating in any other clinical research trial for the duration of the study Exclusion criteria Documented allergies to study product components, soaps, latex, or fragrances History of the following conditions, which may affect response of the skin or interpretation of results: insulin‐dependent diabetes, peripheral vascular disease Participating in a concurrent clinical study involving treatment of the hands Currently using a prescription medication for hand dermatitis
Interventions	Intervention • A test product (mild, moisturising hand cleanser) for all hand cleansing needs during the duration of the study. Control intervention • No Intervention: the control group will continue to use their current cleanser for handwashing
Outcomes	Primary outcome of the trial Efficacy of mild, moisturising hand cleanser for improvement in hand dermatitis from frequent handwashing after 4 weeks
Notes	Sponsor: Wake Forest School of Medicine Study authors were contacted for additional information; they informed us that trial results were marginal and this exploratory study was the terminus of this line of investigation, but we were unable to obtain additional information