Table 2.

Factors affecting PFS in patients with aggressive NHL

Variable	Univariate*		Multivariable†
	HR (95% CI)	P	HR (95% CI)	P
LDH, pre-lymphodepletion‡	1.24 (1.04-1.47)	.02	1.37 (1.14-1.63)	.0006
MCP-1, day 0 (pre-CAR T-cell infusion)§	0.25 (0.10-0.60)	.002	0.29 (0.09-0.90)	.03
IL-7, peak||	0.84 (0.74-0.95)	.01	0.89 (0.77-1.04)	.14

^*Univariate Cox regression model; variables chosen for the final multivariable model are presented (complete univariate results are available in supplemental Table 2).

^†Cox regression model using elastic net was performed to select variables associated with PFS, in which log₁₀ values were used to transform data as appropriate, with 0.001 substituting for values of 0.

^‡Per 100 U/L increment.

^§Per log₁₀ pg/mL serum concentration increment.

^||Per 5 pg/mL serum concentration increment.