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. 2019 Mar 1;23(5):3495–3504. doi: 10.1111/jcmm.14246

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© 2019 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Effects of glycyrrhizin on reactive oxygen species (ROS) in ARPE‐19 cells treated with sodium iodate in vitro. Dichloro‐dihydro‐fluorescein diacetate (DCFH‐DA) staining of ARPE‐19 cells after 24 h of sodium iodate treatment. A, sham; b, retinal pigment epithelium (RPE) treated with sodium iodate (SI); c, RPE treated with sodium iodate plus glycyrrhizin. B, Glycyrrhizin (50 μmol) significantly decreased ROS levels in ARPE‐19 cells after treatment of sodium, compared with sodium iodate control (*P < 0.01).