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. 2019 May 28;4:58. Originally published 2019 Mar 29. [Version 2] doi: 10.12688/wellcomeopenres.15194.2

PMC6484455.1; 2019 Mar 29
PMC6484455.2; 2019 May 28

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Copyright: © 2019 Böhme U et al.

This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Artemis Comparison Tool (ACT) screenshot showing a comparison between 2002 and 2019. Coloured boxes represent genes. The grey blocks between sequences represent sequence similarity (TBLASTX). ( A) A 2-exon gene has been changed into a 22-exon gene (PF3D7_1462500) ( B) Two genes that have been merged (PF3D7_0624900) ( C) A gene that has been split into two genes (PF3D7_0906800, PF3D7_0906700) ( D) Two genes shown in red have been added (PF3D7_1144100, mitochondrial large subunit ribosomal protein; PF3D7_1144300, 60S ribosomal protein L41) ( E) A hypothetical gene (PFI0905w) has been deleted and a ncRNA (PF3D7_0918500, telomerase RNA) has been added. In (E), the six reading frames are shown with tick marks indicating stop codons.