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. 2019 May 28;4:58. Originally published 2019 Mar 29. [Version 2] doi: 10.12688/wellcomeopenres.15194.2

Figure 6. Differences between P. falciparum 3D7 genome version 3.2, a PacBio assembly of P. falciparum 3D7 and two lab strains P. falciparum IT and DD2.

Figure 6.

ACT comparisons between regions of the above genomes. Coloured boxes represent genes. The red blocks between sequences represent sequence similarity (BLASTn). ( A) In the current P. falciparum 3D7 genome assembly v3.2, a hypothetical protein on chromosome 13 is missing. This gene is present in a Pf3D7 PacBio assembly (shown in green). ( B) Comparison between P. falciparum IT chromosome 11 and P. falciparum v3.2 chromosome 11. P. falciparum 3D7 is missing a hypothetical gene on chr11. This gene is present in P. falciparum IT (PfIT_110029300) (shown in green). ( C) Comparison between Pf3D7 v3.2 chromosome 7 and P. falciparum DD2 chromosome 7. The comparison shows the dimorphic gene EBA175 erythrocyte binding antigen-175 (PF3D7_0731500). ( D) Clustalx alignment of EBA175 from PfDD2 and Pf3D7. The area shown is the dimorphic part of the two genes.