Table 2.
Antiretroviral (ARV) prices on the pharmaceutical market and estimates of the lowest price of active pharmaceutical ingredients (APIs), in US dollars [8,26,27].
| Prices per year | Originator prices | Generic on the market | MSF prices |
Estimates of the lower price of API on the market |
|---|---|---|---|---|
| First line | ||||
| NVP + AZT + 3TC | 361 | 90 | 94 | 119 |
| NVP + (TDF + 3TC) | 482 | 64 | 124 | 88 |
| NVP + (TDF + FTC) | 519 | 79 | 88 | 107 |
| EFV + (AZT + 3TC) | 398 | 102 | 164 | 145 |
| EFV + TDF + 3TC | 519 | 80 | 106 | 97 |
| EFV + TDF + FTC | 613 | 77 | 100 | 108 |
| DTG + TDF + 3TC | 482 | 83 | NA | 204 |
| Second line | ||||
| LPV/r + (AZT + 3TC) | 392 | 282 | 316 | 399 |
| LPV/r + (TDF + 3TC) | 513 | 255 | 307 | 344 |
| LPV/r + (TDF + FTC) | 550 | 270 | 307 | 355 |
| DTG + (LPV/r) | 431 | 258 | NA | 434 |
| ATV/r + (AZT + 3TC) | 656 | 265 | 286 | 318 |
| ATV/r + (TDF + 3TC) | 777 | 238 | 277 | 263 |
| ATV/r + (TDF + FTC) | 814 | 253 | 277 | 274 |
| DTG + (ATV/r) | 695 | 241 | NA | 353 |
| DRV/r + (AZT + 3TC) | 892 | 1.074 | NA | 823 |
| DTG + (DRV/r) | 931 | 1.050 | NA | 873 |
| Third line | ||||
| Ral + DRVr | 1.046 | 1.615 | NA | 1696 |
| DTG + DRVr | 931 | 1.050 | NA | 873 |
| Raltegravir | 675 | 608 | 973 | 970 |
NVP= Nevirapine; AZT= Zidovudine; 3TC= Lamivudine; TDF = Tenofovir; FTC= Emtricitabine; EFV= Efavirenz; DTG = Dolutegravir; LPV/r = Lopinavir/ Ritonavir; ATV/r = Atazanavir/ Ritonavir; DRV/r = Darunavir/ Ritonavir; Ral+DRVr = Raltegravir + Darunavir; MSF = Medicin Sans Frontieres; NA = not available.