Supplementary Table 6.

Cytogenetic findings in skin fibroblasts from patients with rheumatoid arthritis and osteoarthritis or unaffected normal controls

	Karyotype/FISH
Subject/diagnosis	Passage 1	Passage 4
EB20/RA	46,XY; FISH:normal	46,XY; FISH:+6 [6%];+12 [8%];incl. polyploid [2%]
EB25/RA	46,XX; FISH:+6 [6%];+9 [6%];incl. polyploid [1%]	n.a.
EB26/RA	46,XY; FISH:normal	n.a.
EB27/RA	46,XX; FISH:normal	n.a.; FISH:normal
EB28/RA	46,XY; FISH:normal	46,XY
EB9/OA	46,XX; FISH:+7 [6%];+8 [7%]	n.a.
EB10/OA	46,XX: FISH:+7 [7%];+8 [7%]	46,XX; FISH:+8 [9%];-18 [8%]
EB11/OA	46,XX; FISH:+18 [8%]	46,XX; FISH:normal
EB12/OA	46,XX	46,XX; FISH:+9 [6%])
EB13/OA	46,XY; FISH:normal	n.a.; FISH:+4 [18%];+7 [17%];+9 [9%];+12 [10%];incl. polyploid [8%]
EB14/OA	n.a.	47,XX,+7[5]/46,XX[3]; FISH:+7 [5%];+8 [5%];+9 [6%];+X [8%];incl. polyploid [2%]
EB15/OA	46,XX; FISH:+7 [6%];+9 [6%];incl. polyploid [4%]	47,XX,+7[2]; FISH:+6 [16%];+7 [45%];+8 [15%];+9 [23%];incl. polyploid [15%]
EB16/OA	46,XX; FISH:+6 [10%];+7 [10%];+8 [22%];+X [24%];incl. polyploid [8%]	n.a.
EB17/OA	46,XX; FISH:normal	46,XX; FISH:+4 [10%];+6 [10%];+8 [11%];+12 [11%];incl. polyploid [9%]
EB18/OA	46,XX; FISH:+8 [5%]	46,XX; FISH:normal
EB19/OA	n.a.; FISH:normal	46,XX; FISH:+7 [7%];+8 [7%];+9 [6%];+12 [10%];incl. polyploid [3%]
EB21/OA	46,XX; FISH:normal	46,XX; FISH:+4 [5%];incl. polyploid [1%]
EB22/OA	46,XY; FISH:normal	46,XY; FISH:+4 [11%];+6 [13%];+7 [12%];+9 [11%];incl. polyploid [10%]
EB24/OA	n.a.; FISH:+4 [7%];+7 [7%];incl. polyploid [1%].	46,XX; FISH:+4 [23%];+6 [24%];+7 [22%];+9 [24%];incl. polyploid [22%]
EB29/OA	n.a.; FISH:normal	n.a.
J5/OA	n.a.; FISH:+4 [5%];incl. polyploid [3%]	n.a.; FISH:+4 [5%];+6 [7%];+7 [5%];+9 [7%];incl. polyploid [5%]
LZ1/Nor	n.a.; FISH:normal	n.a.
LZ2/Nor	46,XX; FISH:normal	n.a.
LZ3/Nor	46,XY; FISH:normal	n.a.
LZ5/Nor	46,XY	n.a.

Nor = normal; OA = osteoarthritis; RA = rheumatoid arthritis; n.a. = not analysed (Karyotype and/or FISH).