Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 25;24(3):362–385. doi: 10.1177/2472555218822098

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Society for Laboratory Automation and Screening

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 1. — (A) Structure of the α7-nAChR. A comparative model based on the homologue protein from Erwinia chrysanthemi (Protein Data Bank code 2VL0), side view. Figure adapted from Taly et al.²⁴ (B) X-ray structure of mouse 5-HT₃R in complex with the VHH15 stabilizing nanobody (Protein Data Bank code 4PIR, 3.50 Å resolution). Side view picture is shown. Figure adapted from Hassaine et al.²¹⁴ (C,D) From x-ray structure of Lymnea stagnalis AChBP (Protein Data Bank code 1I9B, 2.7 Å resolution). (C) Top view, five subunits displayed. (D) Side view, displaying the ligand binding site between two subunits. Figures adapted from Brejc et al.²¹⁵ License agreements for using these figures (A–D) were provided by the Copyright Clearance Center (CCC).