Table 2:

LHR in treatment in hidradenitis suppurativa

S/No.	Study (reference)	Patient no.	Laser parameters	Treatment sittings	Follow-up	Outcome	Adverse effects
1	Downs et al.[26]	1	Diode 14 J/cm2; 50ms, 6 mm	4	None	Decreased erythema and tenderness	Pain during treatment
2	Highton et al.[25]	17	IPL (420nm); 7–10 J/ cm2, 30–50 ms	8	12 months	Significant improvement of treated site compared to control and maintained in F/U period	Erythema posttreatment
3	Mahmoud et al.[28]	17	Nd:YAG; 40–50 J/cm2, 20ms, 10mm (skin types I–III); 25–35 J/ cm2, 35ms, 10mm (skin types IV–VI)	4	2 months	Progressive reduction in disease activity; remission maintained in follow-up period	40% patients experienced periprocedural pain
4	Tierney et al.[24]	17	Nd:YAG; 40–50 J/cm2, 20ms, 10mm (skin types I–III); 25–35 J/ cm2, 35ms, 10mm (skin types IV–VI)	3	1 month	Statistically significant improvement in HS severity of 65.3% averaged over all body sites treated (LHR + topical antibiotics) compared to control (topical antibiotics) at 3 months	Initial worsening of inflammation
5	Koch et al.[23]	1	Alexandrite; 15–22 J/ cm2, 20ms, 15 mm	6	10 months	Excellent response	—
6	Jain et al.[29]	4	Nd:YAG+ CO2 laser	4–5	3 years	None showed any recurrence	—
7	Xu et al.[27]	20	Nd:YAG	2	2 months	Significant improvement of treated site compared to control at 2 months; clinicopathologic correlation between disease activity and histological characteristics following laser treatment was also noted	Initial worsening of inflammation

HS = hidradenitis suppurativa; IPL = intense pulse light; LHR = laser hair removal; Nd:YAG = neodymium:yttrium aluminum garnet