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. 2019 Jan 25;2(1):e187399. doi: 10.1001/jamanetworkopen.2018.7399

Table 2. Benzodiazepine Visit Rate by Indication.

Indicationa No. of Benzodiazepine Visits,
1 Million
Unadjusted Estimated Benzodiazepine Visit Rate, % (95% CI)
2003 2015 2003 2015 P Valueb Adjusted OR (95% CI)c
Anxiety and depression 12.8 23.7 26.6 (22.6-31.0) 33.5 (28.8-38.6) .003 1.43 (1.05-1.95)
Back and chronic pain 4.9 15.1 3.6 (2.6-4.9) 8.5 (6.0-11.9) <.001 2.65 (1.65-4.26)
Insomnia 2.1 3.4 26.9 (19.3-36.0) 25.6 (15.3-39.6) .72 0.94 (0.46-1.92)
Neurologicd 3.3 5.0 6.8 (4.8-9.5) 8.7 (6.2-12.1) <.001 1.37 (0.85-2.22)
Other 9.1 24.5 1.8 (1.4-2.2) 4.4 (3.7-5.2) <.001 2.50 (1.90-3.29)

Abbreviation: OR, odds ratio.

a

A visit can be ascribed to multiple diagnoses.

b

Calculated using χ2 trend test.

c

Adjusted for age, sex, race, insurance, region, and location.

d

Includes headache, seizures, vertigo, and movement disorders.