Table 3. Univariate Sensitivity Analyses of Acute Pain Descriptors as Determinants of Remote Pain Cessation, Opioid Cessation, and Full Recovery After Surgery.

Predictor	HR (95% CI)	P Value	AIC
Sensitivity Analysis for Time to Pain Cessationa
Postoperative day 10 pain score
Worst	0.83 (0.78-0.87)	<.001	1843.229
Average	0.81 (0.76-0.87)	<.001	1855.158
Current	0.87 (0.82-0.93)	<.001	1872.931
Worst pain scores over 10 d
Median	0.88 (0.83-0.94)	<.001	2061.154
Mean	0.87 (0.83-0.93)	<.001	2061.725
Average pain scores over 10 d
Mean	0.87 (0.80-0.95)	.001	2067.125
Median	0.89 (0.82-0.96)	.004	2069.435
Current pain scores over 10 d
Mean	0.91 (0.84-0.99)	.02	2072.804
Median	0.93 (0.86-1.00)	.04	2073.811
High pain cluster of pain trajectories
Average	0.63 (0.50-0.80)	<.001	2315.394
Current	0.71 (0.56-0.89)	.003	2320.682
Worst	0.69 (0.54-0.89)	.004	2321.204
Linear slope of the pain trajectories
Worst	0.68 (0.46-1.00)	.05	2325.657
Average	0.70 (0.44-1.12)	.14	2327.304
Current	0.83 (0.54-1.28)	.40	2328.814
Sensitivity Analysis for Time to Opioid Cessationa
Postoperative day 10 pain score
Worst	0.84 (0.80-0.89)	<.001	1883.381
Average	0.82 (0.76-0.88)	<.001	1894.527
Current	0.85 (0.79-0.91)	<.001	1903.222
Worst pain scores over 10 d
Mean	0.85 (0.79-0.90)	<.001	2087.508
Median	0.86 (0.82-0.91)	<.001	2089.049
Average pain scores over 10 d
Mean	0.85 (0.79-0.92)	<.001	2098.918
Median	0.87 (0.80-0.93)	<.001	2099.983
Current pain scores over 10 d
Mean	0.87 (0.81-0.95)	.001	2104.030
Median	0.89 (0.83-0.96)	.002	2105.688
High pain cluster of pain trajectories
Average	0.52 (0.41-0.67)	<.001	2342.622
Worst	0.57 (0.44-0.73)	<.001	2351.640
Current	0.66 (0.52-0.83)	<.001	2368.149
Linear slope of the pain trajectories
Average	0.77 (0.47-1.26)	.30	2369.041
Worst	0.81 (0.55-1.21)	.30	2369.094
Current	0.81 (0.51-1.27)	.36	2369.313
Sensitivity Analysis for Time to Recoverya
Postoperative day 10 pain score
Worst	0.91 (0.86-0.96)	<.001	1671.220
Average	0.89 (0.83-0.95)	.001	1672.025
Current	0.93 (0.87-0.99)	.03	1678.362
Worst pain scores over 10 d
Mean	1.01 (0.94-1.07)	.88	1868.195
Median	1.00 (0.95-1.06)	.90	1868.201
Average pain scores over 10 d
Median	1.02 (0.95-1.10)	.64	1867.996
Mean	1.02 (0.94-1.10)	.66	1868.023
Current pain scores over 10 d
Mean	1.04 (0.96-1.13)	.31	1867.194
Median	1.03 (0.96-1.11)	.46	1867.668
High pain cluster of pain trajectories
Average	0.89 (0.69-1.14)	.36	2066.712
Worst	1.04 (0.79-1.36)	.78	2067.480
Current	1.01 (0.79-1.28)	.97	2067.559
Linear slope of the pain trajectories
Average	0.64 (0.37-1.11)	.11	2065.001
Current	0.69 (0.41-1.16)	.16	2065.631
Worst	0.78 (0.52-1.18)	.24	2066.192

Abbreviations: AIC, Akaike information criterion; HR, hazard ratio.

^aStratification by type of surgery.