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. 2019 Mar 15;2(3):e191938. doi: 10.1001/jamanetworkopen.2019.1938

Table. Patient Characteristics.

Characteristic 1995-1998 (n = 1 012 897) 1999-2002 (n = 999 009) 2003-2006 (n = 919 981) 2007-2010 (n = 742 812) 2011-2014 (n = 692 786) Aggregated (N = 4 367 485)
Demographic characteristics and comorbidities, No. (%)
Age, mean (SD), y 77.3 (7.3) 78.4 (7.8) 78.6 (8.1) 78.6 (8.5) 78.1 (8.6) 78.2 (8.0)
Female 505 015 (49.9) 505 786 (50.6) 461 401 (50.2) 366 863 (49.4) 326 029 (47.1) 2 165 094 (49.6)
White 914 985 (90.3) 889 941 (89.1) 809 239 (88.0) 650 931 (87.6) 599 774 (86.6) 3 864 870 (88.5)
Black 61 039 (6.0) 68 416 (6.8) 67 842 (7.4) 56 564 (7.6) 55 536 (8.0) 309 397 (7.1)
Other race 31 440 (3.1) 40 652 (4.1) 42 900 (4.7) 35 317 (4.8) 37 476 (5.4) 193 218 (4.4)
Heart failure 134 488 (13.3) 144 952 (14.5) 136 957 (14.9) 106 029 (14.3) 92 039 (13.3) 614 465 (14.1)
Myocardial infarction 46 391 (4.6) 49 164 (4.9) 45 062 (4.9) 36 292 (4.9) 33 072 (4.8) 209 981 (4.8)
Unstable angina 56 939 (5.6) 49 009 (4.9) 33 820 (3.7) 21 471 (2.9) 17 680 (2.6) 178 919 (4.1)
Chronic atherosclerosis 680 245 (67.2) 655 429 (65.6) 630 149 (68.5) 519 313 (69.9) 496 177 (71.6) 2 981 313 (68.3)
Cardiorespiratory disease 21 737 (2.1) 25 313 (2.5) 27 667 (3.0) 34 521 (4.6) 36 762 (5.3) 146 000 (3.3)
Hypertension 485 258 (47.9) 537 800 (53.8) 532 660 (57.9) 477 564 (64.3) 468 670 (67.7) 2 501 952 (57.3)
Stroke 20 517 (2.0) 20 595 (2.1) 17 841 (1.9) 13 913 (1.9) 12 405 (1.8) 85 271 (2.0)
Cerebrovascular disease 40 588 (4.0) 52 259 (5.2) 42 135 (4.6) 30 768 (4.1) 27 183 (3.9) 192 933 (4.4)
Renal failure 31 353 (3.1) 45 552 (4.6) 64 392 (7.0) 87 220 (11.7) 92 187 (13.3) 320 704 (7.3)
Chronic obstructive pulmonary disease 204 168 (20.2) 227 051 (22.7) 223 856 (24.3) 158 333 (21.3) 138 327 (20.0) 951 735 (21.8)
Pneumonia 91 977 (9.1) 126 982 (12.7) 131 896 (14.3) 114 628 (15.4) 101 380 (14.6) 566 863 (13.0)
Protein calorie malnutrition 9810 (1.0) 24 282 (2.4) 27 512 (3.0) 33 123 (4.5) 36 604 (5.3) 131 331 (3.0)
Dementia 50 051 (4.9) 92 066 (9.2) 95 134 (10.3) 81 219 (10.9) 47 194 (6.8) 365 664 (8.4)
Functional disability 18 090 (1.8) 25 823 (2.6) 21 925 (2.4) 18 419 (2.5) 17 522 (2.5) 101 779 (2.3)
Peripheral vascular disease 52 800 (5.2) 61 473 (6.2) 60 671 (6.6) 49 220 (6.6) 41 585 (6.0) 265 749 (6.1)
Metastatic cancer 23 717 (2.3) 62 611 (6.3) 60 943 (6.6) 50 061 (6.7) 44 158 (6.4) 241 490 (5.5)
Trauma in past year 41 581 (4.1) 51 883 (5.2) 56 273 (6.1) 45 483 (6.1) 37 689 (5.4) 232 909 (5.3)
Major psychiatric disorder 12 524 (1.2) 18 274 (1.8) 16 481 (1.8) 14 918 (2.0) 15 113 (2.2) 77 310 (1.8)
Liver disease 4222 (0.4) 5673 (0.6) 6337 (0.7) 5102 (0.7) 5751 (0.8) 27 085 (0.6)
Depression 22 740 (2.2) 44 332 (4.4) 48 799 (5.3) 40 341 (5.4) 41 069 (5.9) 197 281 (4.5)
Diabetes 334 688 (33.0) 293 433 (29.4) 277 281 (30.1) 225 956 (30.4) 229 613 (33.1) 1 360 971 (31.2)
Outcomes, % (95% CI)
30-d mortality 19.1 (19.1-19.2) 19.2 (19.2-19.3) 17.1 (17.1-17.2) 15.2 (15.1-15.3) 13.4 (13.3-13.5) 17.2 (17.1-17.2)
In-hospital mortality 14.3 (14.2-14.4) 14.1 (14.0-14.1) 11.5 (11.5-11.6) 9.2 (9.15-9.28) 7.7 (7.63-7.76) 11.7 (11.7-11.8)
30-d readmission 21.3 (21.2-21.4) 21.8 (21.7-21.9) 21.4 (21.3-21.5) 20.2 (20.1-20.3) 17.4 (17.3-17.5) 20.4 (20.3-20.4)
Discharge to home 44.5 (44.4-44.6) 46.1 (46.0-46.2) 45.1 (45.0-45.2) 46.9 (46.8-47.0) 50.2 (50.1-50.3) 46.3 (46.3-46.3)
Discharge to home with home health service 9.1 (9.06-9.17) 9.6 (9.51-9.62) 12.1 (12.1-12.2) 13.2 (13.2-13.3) 13.2 (13.1-13.3) 11.2 (11.2-11.2)
Discharge to skilled nursing home 10.5 (10.4-10.5) 14.0 (13.9-14.1) 15.9 (15.8-16.0) 16.6 (16.6-16.7) 15.4 (15.3-15.5) 11.8 (11.8-11.9)
Discharge to hospice 0 (0.01-0.01) 0.3 (0.30-0.32) 1.7 (1.64-1.69) 2.7 (2.71-2.78) 3.0 (2.96-3.04) 1.4 (1.35-1.38)
Transferred to another acute-care hospital 19.0 (18.9-19.1) 11.7 (11.6-11.7) 8.8 (8.70-8.82) 6.6 (6.57-6.68) 5.6 (5.59-5.70) 10.9 (10.9-11.0)
Length of stay, mean (SD), d 6.5 (6.0) 6.5 (6.7) 6.2 (6.5) 5.7 (5.9) 5.1 (5.2) 6.1 (6.2)