Table 2. Observed Outcomes by Treatment Group Using Testing Data, Stratified by Subgroup Identified Using Training Data.

Primary Composite Outcome^a	No. of Patients (No. of Events)		HR (95% CI)	P Value
Primary Composite Outcome^a	Treated	Control	HR (95% CI)	P Value
Overall	2354 (121)	2326 (160)	0.7 (0.6-0.9)	.02
Subgroups				.02^b
Current smokers with baseline systolic blood pressure >144 mm Hg	110 (12)	126 (6)	10.6 (1.3-86.1)	.03
Remainder of trial population	2244 (109)	2200 (154)	0.7 (0.5-0.9)	.003

Abbreviation: HR, hazard ratio.

^{^a}

Includes myocardial infarction, other acute coronary syndromes, stroke, heart failure, or death due to cardiovascular causes.

^{^b}

P value for the interaction term; false discovery rate for the interaction term is 0.007.