Table 1.
Summary Table of the MoA Dataset.
| Compound | Number of Concentrations | Mechanism of Action (MoA) | Replicates | Number of Images |
|---|---|---|---|---|
| Cytochalasin B | 2 | Actin disruption | 3 | 24 |
| Cytochalasin D | 1 | Actin disruption | 3 | 12 |
| Latrunculin B | 2 | Actin disruption | 3 | 24 |
| AZ-A | 6 | Aurora kinase inhibition | 3 | 72 |
| AZ258 | 3 | Aurora kinase inhibition | 3 | 36 |
| AZ841 | 3 | Aurora kinase inhibition | 3 | 36 |
| Mevinolin/lovastatin | 3 | Cholesterol lowering | 3 | 36 |
| Simvastatin | 3 | Cholesterol lowering | 3 | 36 |
| Chlorambucil | 1 | DNA damage | 3 | 12 |
| Cisplatin | 1 | DNA damage | 3 | 12 |
| Etoposide | 3 | DNA damage | 3 | 36 |
| Mitomycin C | 4 | DNA damage | 3 | 48 |
| Camptothecin | 3 | DNA replication | 3 | 36 |
| Floxuridine | 2 | DNA replication | 3 | 24 |
| Methotrexate | 1 | DNA replication | 3 | 12 |
| Mitoxantrone | 2 | DNA replication | 3 | 24 |
| AZ-C | 7 | Eg5 inhibition | 3 | 84 |
| AZ138 | 5 | Eg5 inhibition | 3 | 60 |
| AZ-J | 3 | Epithelial | 3 | 36 |
| AZ-U | 3 | Epithelial | 3 | 36 |
| PP-2 | 2 | Epithelial | 2 | 16 |
| Alsterpaullone | 2 | Kinase inhibition | 2 | 16 |
| Bryostatin | 1 | Kinase inhibition | 2 | 8 |
| PD-169316 | 2 | Kinase inhibition | 2 | 16 |
| Colchicine | 1 | Microtubule destabilization | 3 | 12 |
| Demecolcine | 4 | Microtubule destabilization | 3 | 48 |
| Nocodazole | 2 | Microtubule destabilization | 3 | 24 |
| Vincristine | 7 | Microtubule destabilization | 3 | 84 |
| Docetaxel | 3 | Microtubule stabilization | 3 | 36 |
| Epothilone B | 3 | Microtubule stabilization | 3 | 36 |
| Taxol | 3 | Microtubule stabilization | 3 | 36 |
| ALLN | 2 | Protein degradation | 3 | 24 |
| lactacystin | 1 | Protein degradation | 3 | 12 |
| MG-132 | 2 | Protein degradation | 3 | 24 |
| Proteasome inhibitor I | 2 | Protein degradation | 3 | 24 |
| Anisomycin | 2 | Protein synthesis | 3 | 24 |
| Cyclohexamide | 3 | Protein synthesis | 3 | 36 |
| Emetine | 3 | Protein synthesis | 3 | 36 |
The “Number of Images” column represents the number of images before augmentation (through cropping).