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Summary of TEAEs in ibrutinib-treated patients
| n (%) | Ibrutinib+BR (N = 287) |
|---|---|
| TEAEs | 282 (98.3) |
| Grade ≥3 | 254 (88.5) |
| Drug related | 246 (85.7) |
| Serious TEAEs | 176 (61.3) |
| Grade ≥3 | 157 (54.7) |
| Drug related | 102 (35.5) |
| TEAEs leading to treatment discontinuation | 46 (16.0) |
| TEAEs with outcome of death | 28 (9.8) |
BR bendamustine and rituximab, TEAE treatment-emergent adverse event
