Table 1.
Patients (n = 220) | Controls (n = 299) | p value | |
---|---|---|---|
Mean age, year (SD) | 55.0 (9.37) | 47.5 (13.1) | < 0.001 |
Men, n (%) | 173 (78.6) | 138 (46.2) | < 0.001 |
Statin use at blood draw, n (%) | 18 (8.2) | 22 (7.4) | 0.717 |
Mean BMI, kg/m2 (SD) | 26.63 (3.98) | 25.32 (4.24) | < 0.001 |
Normal weight, n (%) | 87 (40.1) | 153 (52.4) | 0.016 |
Overweight, n (%) | 91 (41.9) | 104 (35.6) | 0.028 |
Obesity, n (%) | 39 (18.0) | 35 (12.0) | 0.012 |
Smoking history, n (%) | 139 (63.2) | 174 (58.8) | 0.312 |
Cholesterol, mmol/L, mean (SD) | 5.63 (1.09) | 5.54 (1.10) | 0.333 |
Triglycerides, mmol/L, median (IQR) | 1.53 (1.01–2.22) | 1.23 (0.97–1.88) | 0.002 |
HDLc, mmol/L, mean (SD) | 1.27 (0.36) | 1.37 (0.40) | 0.004 |
LDLc, mmol/L, mean (SD) | 3.48 (0.94) | 3.49 (1.00) | 0.912 |
Remnant cholesterol, mmol/L, mean (SD) | 0.88 (0.72) | 0.68 (0.36) | < 0.001 |
ApoA1, g/L, mean (SD) | 1.24 (0.24) | 1.53 (0.31) | 0.001 |
ApoB, g/L, mean (SD) | 1.18 (0.25) | 1.08 (0.29) | < 0.001 |
ApoCI, mg/L, mean (SD) | 20.03 (7.82) | 21.38 (5.33) | 0.020 |
ApoCII, mg/L, median (IQR) | 36.10 (20.99–58.71) | 34.32 (19.38–55.24) | 0.440 |
ApoCIII, mg/L, median (IQR) | 86.89 (65.48-117.08) | 97.33 (77.56–119.90) | 0.002 |
ApoE, mg/L, mean (SD) | 33.15 (26.6) | 30.71 (13.04) | 0.170 |
Ratio apoB/apoA1, mean (SD) | 1.00 (0.29) | 0.74 (0.25) | 0.001 |
Non-HDLc, mmol/L, mean (SD) | 4.36 (1.07) | 4.17 (1.13) | 0.050 |
Categorical variables expressed by number (%)
Numerical variables expressed by mean (SD) or median (IQR)
Comparisons between groups were made using Chi square test for categorical variables and independent T test or Mann–Whitney U test for continuous variables
BMI body mass index, HDLc high-density-lipoprotein cholesterol, LDLc low-density-lipoprotein cholesterol, Apo apolipoprotein