. 2019 Mar 6;4(4):314–320. doi: 10.1001/jamacardio.2019.0179

Table 3. Multivariable Cox Regression Models for Major Adverse Cardiac Event, All-Cause Death, and Cardiovascular Death.

Covariate	Hazard Ratio (95% CI)	P Value
Major adverse cardiac event
Longitudinal hsCRP level^a	1.15 (1.09-1.21)	<.001
Baseline hsCRP level (log transformed)^a	1.36 (1.13-1.63)	.001
Male	0.68 (0.47-0.99)	.04
Previously documented myocardial infarction	1.73 (1.18-2.53)	.005
Unstable angina requiring hospitalization	1.65 (1.08-2.53)	.02
History of congestive heart failure	1.65 (1.12-2.43)	.01
History of valvular disease	2.21 (1.07-4.56)	.03
All-cause death
Longitudinal hsCRP level^a	1.25 (1.18-1.32)	<.001
Baseline hsCRP level (log transformed)^a	1.58 (1.07-2.35)	.02
Age	1.06 (1.01-1.10)	.008
Previously documented myocardial infarction	2.80 (1.22-6.45)	.015
History of congestive heart failure	2.38 (1.05-5.43)	.04
Cardiovascular death
Longitudinal hsCRP level^a	1.26 (1.19-1.34)	<.001
Baseline hsCRP level (log transformed)^a	1.61 (1.07-2.41)	.02
Age	1.07 (1.03-1.11)	.002
Previously documented myocardial infarction	3.29 (1.37-7.94)	.008
History of congestive heart failure	2.64 (1.12-6.22)	.03

Abbreviation: hsCRP, high-sensitivity C-reactive protein.

^{^a}

Continuous covariates were per SD. Model was adjusted for drug treatment.