Figure 3.

COX2 expression is upregulated in response to the binary PAH mixture in C10 cells. A, Immunoblots of COX2 and β-actin protein in C10 exposed to DMSO control (C) or binary PAH mixture (P; 40 µM) for 0.5–8 h. B, Densitometric analysis of COX2 protein expression normalized to β-actin shows a biphasic increase at 2 and 8 h following exposure to PAH mixture (40 µM; 1:1 ratio of 1-methylanthracene and fluoranthene). Mean ± SE; n = 3, repeated twice. *p < .05, significantly different from control.