Table 1. Comparison of scalding and laser-induced rat models.
Model | Method | Advantage | Disadvantage |
---|---|---|---|
Scalding model | Direct application of hot water to skin | · Most common type of burns | · Difficult to maintain uniform high temperature and to predict wound |
· Constant surface temperature | · Dangerous to investigators | ||
· Standardized model | · Complex procedures | ||
| |||
Laser-induced model | Irradiation of 1470 nm light on skin | · Constant heat flux | · Laser system required |
· Easy to control thermal injury | · Difficult to develop large wound area | ||
· Simple procedure | · May cause carbonization |