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. 2019 Mar 22;10(4):1965–1977. doi: 10.1364/BOE.10.001965

Table 1. Comparison of scalding and laser-induced rat models.

Model Method Advantage Disadvantage
Scalding model Direct application of hot water to skin · Most common type of burns · Difficult to maintain uniform high temperature and to predict wound
· Constant surface temperature · Dangerous to investigators
· Standardized model · Complex procedures

Laser-induced model Irradiation of 1470 nm light on skin · Constant heat flux · Laser system required
· Easy to control thermal injury · Difficult to develop large wound area
· Simple procedure · May cause carbonization