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. 2019 Apr 26;19:134. doi: 10.1186/s12887-019-1499-2

Table 3.

Main causes of drug related problems (DRP) according to the PCNE classification version 6.2

Causes of DRP (n = 1142) n %
C3- Dose selection 454 39.7
 C3.1- Drug dose too low 154 13.5
 C3.3- Dosage regimen not frequent enough 124 10.9
 C3.2- Drug dose too high 117 10.2
 C3.7- Deterioration or improvement of disease state requiring dose adjustment 38 3.3
 C3.4- Dosage regimen too frequent 21 1.8
C5- Drug use process 373 32.7
 C5.5- Wrong drug administered 164 14.4
 C5.1- Inappropriate timing of administration and/or dosing intervals 103 9.0
 C5.4- Drug not administered at all 70 6.1
 C5.2- Drug under-administered 36 3.2
C6- Logistics 187 16.4
 C6.2- Prescription error (necessary information missing) 157 13.8
 C6.1- Prescribed drug not available 30 2.6
C1- Drug selection 52 4.5
 C1.3- Inappropriate combination of drugs, or drugs and food 35 3.1
 C1.8- Synergistic or preventive drug required and not given 6 0.5
 C1.4- Inappropriate duplication of therapeutic group or active ingredient 4 0.3
 C1.5- Indication for drug treatment not noticed 4 0.3
 C1.2- No indication for drug 2 0.2
 C1.1- Inappropriate drug 1 0.1
C8- Other 76 6.7
 C8.1- Others specific causes 76 6.7
 C8.2- No obvious cause 0 0