Table 1.

Concentrations of ceftolozane and tazobactam in pre-filter and post-filter plasma samples obtained after the fourth dose of 2 g/1 g ceftolozane-tazobactam administered as intravenous 1-h infusion

Sampling time	Ceftolozane (mg/L)		Tazobactam (mg/L)
	Pre-filter	Post-filter	Pre-filter	Post-filter
0 h (pre dose)	41.9	20.7	10.6	5.8
1.5 h post dose	89.1	45.2	28.3	12.2
2 h post dose	80.3	38.4	21.6	10.3
2.5 h post dose	77.1	36.1	19.0	9.0
3 h post dose	73.8	34.7	16.3	8.2
5 h post dose	66.6	30.6	14.2	7.4
7 h post dose	60.2	28.7	12.7	6.0
8 h post dose	55.8	25.8	11.4	5.1