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(A) Bacteriophage QβCP, GFP coexpression system, and gVLPs complex self-assembly process in vivo. (B) Modification of the CPPs on gVLPs (CPP-gVLPs), 68Ga-DOTA labelling (68Ga-DOTA labelled CPP-gVLPs), and EPI loading in 68Ga-DOTA labelled CPP-gVLPs (68Ga-DOTA labelled EPI@CPP-gVLPs). (C) Schematic of 68Ga-DOTA labelled EPI@CPP-gVLPs infusion in a brain tumor by CED.
