. 2001 Oct 2;4(1):54–58. doi: 10.1186/ar383

Table 1.

Arthritis is exacerbated in IL-4-deficient mice and suppressed in IFN-γ-deficient mice

Mice	Incidence (arthritis/total) (%)	Arthritis score of diseased mice^a	Day of onset^b
Wild-type	9/12 (75)	5.2 ± 2.5	11.8 ± 6.6
IL-4^-/-	9/9 (100)	9.6 ± 1.1^*	9.5 ± 6.0
IFN-γ-/-	5/22 (22)	2.4 ± 2.0^*	36.8 ± 6.2^**

^aMean arthritic score for wild-type and IL-4-deficient mice was maximum at day 23 and for the IFN-γ-deficient mice at day 41 after the last immunization with PG. ^bDays from last immunization with PG to onset of disease. ^*Score differed significantly from that for wild-type mice (P < 0.05). ^**Time to onset of disease differed significantly from that in wild-type mice (P < 0.002).