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A high-salt diet significantly increased blood pressure among CYP2C11-null rats compared with a normal diet (female, P < 0.01, male, P < 0.05; n = 10). The increase in CYP2C11-null females was significantly higher than in CYP2C11-null males and WT females (P < 0.01, n = 10). All data are expressed as mean ± standard deviation. *P < 0.05, **P < 0.01.
