Table 1.
Demographic and baseline characteristics of patients with gastric cancer
| Parameter | The Pooled (∑n≥15) |
Study group (∑N1≥15) |
Control group (∑N1<15) |
P value |
|---|---|---|---|---|
| (n=1003) | (n=635) | (n=368) | ||
| Age, yrs | 56.6±12.3 | 56.6±12.0 | 56.6±12.8 | 0.931 |
| ≤65 | 741 (73.9) | 475 (74.8) | 266 (72.3) | 0.421 |
| >65 | 262 (26.1) | 160 (25.2) | 102 (27.7) | |
| Gender, Male:Female | 663:340 | 422:213 | 241:127 | 0.782 |
| BMI, kg/m2 | 21.6±3.3 | 21.5±3.4 | 21.7±3.1 | 0.638 |
| Comorbidity (yes), n (%) | ||||
| HTN | 260 (24.8) | 152 (23.9) | 98 (26.6) | 0.364 |
| DM | 115 (11.5) | 65 (10.2) | 50 (13.6) | 0.123 |
| Smoke (yes), n (%) | 283 (28.2) | 183 (28.8) | 100 (27.1) | 0.611 |
| Alcohol abuse (yes), n (%) | 190 (18.9) | 123 (19.4) | 67 (18.2) | 0.677 |
| ASA, n (%) | 0.325 | |||
| I+II | 754 (75.2) | 484 (76.2) | 270 (73.4) | |
| III+IV | 249 (24.8) | 151 (23.8) | 98 (26.6) | |
| Albumin level, g/dL | 38.8±6.4 | 38.5±6.9 | 39.3±5.5 | 0.057 |
| Tumor Location, n (%) | 0.007 | |||
| Upper 1/3 | 347 (34.6) | 225 (35.4) | 122 (33.1) | |
| Middle 1/3 | 279 (27.8) | 193 (30.4) | 86 (23.4) | |
| Lower 1/3 | 377 (37.6) | 217 (34.2) | 160 (43.5) | |
| Type of Anastomosis, n (%) | 0.629 | |||
| Billroth I | 34 (3.4) | 23 (3.6) | 11 (3.0) | |
| Billroth II | 340 (33.9) | 209 (32.9) | 131 (35.6) | |
| Roux-en-Y | 629 (62.7) | 403 (63.5) | 226 (61.4) | |
| Lymphadenectomy, n (%) | 0.800 | |||
| D1 | 47 (4.7) | 28 (4.4) | 19 (5.2) | |
| D2 | 784 (78.2) | 500 (78.8) | 284 (77.1) | |
| D2 plus* | 172 (17.1) | 107 (16.8) | 65 (17.7) | |
| Depth of invasion, n (%) | 0.377 | |||
| pT0-1 | 157 (15.6) | 97 (15.3) | 60 (16.3) | |
| pT2 | 103 (10.3) | 58 (9.1) | 45 (12.2) | |
| pT3 | 553 (55.1) | 360 (56.7) | 193 (52.5) | |
| pT4 | 190 (19.0) | 120 (18.9) | 70 (19.0) | |
| Number of LNs retrieval, n | 32.2±14.2 | 37.2±14.7 | 23.6±8.0 | <0.001 |
| N1 stations | 18.9±10.2 | 24.3±8.7 | 9.5±3.6 | <0.001 |
| N2 stations | 9.4±7.0 | 9.7±7.6 | 8.9±5.9 | 0.077 |
| N2 plus stations | 1.7±3.9 | 1.8±4.3 | 1.6±3.1 | 0.352 |
| Number of Positive LNs, n | 7.3±11.1 | 8.9±12.8 | 4.7±6.3 | <0.001 |
| Histopathological type, n (%) | 0.149 | |||
| Well diff. | 81 (8.1) | 55 (8.7) | 26 (7.1) | |
| Moderate diff. | 347 (34.6) | 206 (32.4) | 141 (38.3) | |
| Poor diff. | 575 (57.3) | 374 (58.9) | 201 (54.6) | |
| pTNM Stage, n (%) | <0.001 | |||
| I | 187 (18.6) | 100 (15.7) | 87 (23.6) | |
| II | 425 (42.4) | 263 (41.4) | 162 (44.0) | |
| III | 391 (39.0) | 272 (42.9) | 119 (32.4) |
Patients were divided into study group and control group according to the number of N1 station retrieval (cutoff value, 15). Data present with mean±SD or number (percentage of column). Abbreviations: BMI, body mass index; HTN, hypertension; DM, diabetes mellitus; ASA, American society of anesthesia; diff., differentiation. * D2 plus means extended lymphadenectomy beyond D2 stations during radical gastrectomy.