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. Author manuscript; available in PMC: 2019 Apr 26.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2018 Jan 9;7(2):10.1002/wdev.309. doi: 10.1002/wdev.309

FIGURE 2.

FIGURE 2

Interaction of cellular and humoral factors in wound healing. Note the key role of the macrophage. FGF2 = basic fibroblast growth factor; EGF = epidermal growth factor; GAGs = glycosaminoglycans; H2O2 = hydrogen peroxide; IFNG = interferon-gamma; IGF = insulin-like growth factor; IL1 = interleukin-1; IL6 = interleukin-6; KGF = keratinocyte growth factor; O2− = superoxide; -OH = hydroxyl radical; PDGF = platelet-derived growth factor; PGE2 = prostaglandin E2; TGFB = transforming growth factor-beta; TNFA = tumor necrosis factor-alpha; VEGF = vascular endothelial growth factor (Reprinted with permission from Townsend Beauchamp, Evers, and Mattox (2017). Copyright 2017 Elsevier)