Table 1.
Physiological parameters - body and muscle weights and BUN in various cohorts
| Sham | CKD | CKD+Exo/ ctrl | CKD+Exo/ miR-26a | |
|---|---|---|---|---|
| Baseline B.W. (g) | 22.6 ± 1.9 | 22.7 ± 1.8 | 22.5 ± 2.3 | 22.9 ± 1.6 |
| Terminal B.W. (g) | 24.2 ± 2.5 | 19.5 ± 3.8* | 20.5 ± 2.3* | 22.9 ± 2.6 |
| TA weight (mg) | 35.1 ± 1.1 | 28.7 ± 0.4* | 28.8 ± 0.5* | 32.1 ± 0.6# |
| Soleus weight (mg) | 10.5 ± 0.1 | 8.7 ± 0.2 | 8.1 ± 0.5* | 9.8 ± 0.8*# |
| EDL weight (mg) | 10.3 ± 0.2 | 8.9 ± 0.6 | 8.2 ± 0.7* | 9.7 ± 0.3*# |
| BUN (mg/dL) | 21.3 ± 4.3 | 88.9 ± 11.6* | 86.2 ± 8.7* | 72.3 ± 6.5* |
Data are presented as the mean ± se; P < 0.05 is significant (*vs. sham, #vs. CKD), n=12/group; B.W.: body weight; TA: tibialis anterior; EDL: extensor digitorum longus; BUN: blood urea nitrogen