Table.
Treatment |
IOP |
IOP 20 Hours |
ΔIOP |
C0 |
Cd21 |
Cd/Co |
% Change |
AP5 responders | |||||||
AP5 | 11.6 | 16.0 | 4.4 | 0.39 | 0.28 | 0.72 | −28 |
AP5 | 10.0 | 13.9 | 3.9 | 0.45 | 0.32 | 0.72 | −28 |
AP5 | 18.3 | 29.5 | 11.2 | 0.25 | 0.15 | 0.62 | −38 |
AP5 | 13.3 | 21.4 | 8.1 | 0.34 | 0.21 | 0.61 | −39 |
AP5 | 9.7 | 11.6 | 1.9 | 0.46 | 0.39 | 0.85 | −15 |
Mean ± SEM | 5.9 ± 1.6* | 0.70 ± 0.04* | −30 ± 4 | ||||
AP5 nonresponders | |||||||
AP5 | 7.2 | 7.2 | 0 | 0.62 | 0.62 | 1.00 | 0 |
AP5 | 9.8 | 8.9 | −0.9 | 0.46 | 0.51 | 1.11 | 11 |
AP5 | 6.0 | 4.8 | −1.1 | 0.75 | 0.92 | 1.22 | 22 |
AP5 | 9.1 | 7.0 | −2.1 | 0.50 | 0.64 | 1.30 | 30 |
AP5 | 23.9 | 17.9 | −6.0 | 0.19 | 0.25 | 1.33 | 33 |
AP5 | 7.2 | 6.1 | −1.1 | 0.63 | 0.74 | 1.17 | 17 |
AP5 | 24.2 | 16.1 | −8.1 | 0.19 | 0.28 | 1.47 | 47 |
Mean ± SEM | −2.8 ± 1.1 | 1.23 ± 0.06* | 23 ± 6 | ||||
All IgG | |||||||
IgG | 7.2 | 7.0 | −0.2 | 0.63 | 0.64 | 1.02 | 2 |
IgG | 11.1 | 9.7 | −1.4 | 0.41 | 0.46 | 1.12 | 12 |
IgG | 8.5 | 9.5 | 1.0 | 0.53 | 0.47 | 0.89 | −11 |
IgG | 43.4 | 38.9 | −4.5 | 0.10 | 0.12 | 1.20 | 20 |
IgG | 10.9 | 10.8 | −0.1 | 0.41 | 0.42 | 1.02 | 2 |
IgG | 12.8 | 8.1 | −4.7 | 0.35 | 0.56 | 1.60 | 60 |
IgG | 18.5 | 24.2 | 5.7 | 0.24 | 0.19 | 0.79 | −21 |
IgG | 29.6 | 21.9 | −7.8 | 0.15 | 0.21 | 1.40 | 40 |
IgG | 18.4 | 17.7 | −0.7 | 0.24 | 0.25 | 1.04 | 4 |
IgG | 14.6 | 15.6 | 1.0 | 0.31 | 0.29 | 0.94 | −6 |
IgG | 11.9 | 13.6 | 1.7 | 0.38 | 0.33 | 0.87 | −13 |
IgG | 7.0 | 5.8 | −1.2 | 0.64 | 0.78 | 1.22 | 22 |
IgG | 21.5 | 18.0 | −3.5 | 0.21 | 0.25 | 1.19 | 19 |
IgG | 12.4 | 7.8 | −4.6 | 0.36 | 0.58 | 1.61 | 61 |
Mean ± SEM | −1.4 ± 0.91 | 1.13 ± 0.07 | 14 ± 7 |
IOP is measured in mm Hg. Co, average baseline outflow facility for 1 hour prior to treatment (μL/min/mm Hg); Cd21, average outflow facility from 20 to 21 hours after exchange (μL/min/mm Hg). % change is the % difference of Cd21/Co.
Significantly different from baseline at P < 0.05.