| Study | Reason for exclusion |
|---|---|
| MDRD 1994 | Fewer than 50 participants in each group with cardiovascular disease at baseline |
| NCT01230216 | Study not completed due to slow patients enrolment |
| PODCAST 2013 | Fewer than 50 participants in each group with cardiovascular disease at baseline. The study is in progress but the recruitment phase has closed |
| REIN‐2 2005 | Fewer than 50 patients in each group with cardiovascular disease at baseline |
| RESTART‐AP 2013 | Study not completed due to lack of funding, according to information from the authors |