Drug	Dose (mg)	Number of		Per cent with outcome		Risk ratio (95% CI)
		Studies	Participants	Active	Placebo
Aspirin	600/650	46	3633	11	9.5	1.2 (1.0 to 1.4)
Aspirin	9200/1000	4	404	26	12	1.6 (1.1 to 2.3)
Celecoxib	200	4	669	16	17	0.9 (0.6 to 1.3)
Celecoxib	400	6	725	34	46	1.0 (0.8 to 1.2)
Dexketoprofen	10/12.5	3	258	9	46	0.6 (0.3 to 1.3)
Dexketoprofen	20/25	5	413	20	46	1.3 (0.8 to 2.1)
Diclofenac fast acting	All doses	5	636	8	46	1.0 (0.6 to 1.8
Diclofenac potassium	All doses	7	1090	8	46	1.0 (0.7 to 1.6)
Diflunisal	250	3	195	3	6	0.5 (0.2 to 1.8)
Diflunisal	500	7	462	18	15	1.3 (0.8 to 1.9)
Diflunisal	1000	6	417	29	16	1.8 (1.2 to 2.6)
Etodolac	50	4	320	8	6	1.4 (0.6 to 3.2)
Etodolac	100	5	459	11	7	1.6 (0.9 to 2.8)
Etodolac	200	7	633	22	17	1.2 (0.9 to 1.7)
Etodolac	400	4	310	28	34	0.8 (0.5 to 1.2)
Etoricoxib	120/180/240	5	1029	32	38	0.9 (0.7 to 1.1)
Fenoprofen	200	4	287	6	6	0.9 (0.4 to 2.1)
Flurbiprofen	25	3	221	14	16	0.9 (0.5 to 1.7)
Flurbiprofen	50	8	564	13	17	0.8 (0.5 to 1.1)
Flurbiprofen	100	5	342	12	12	1.0 (0.6 to 1.8)
Ibuprofen	50	2	225	10	7	1.3 (0.6 to 3.0)
Ibuprofen	100	3	310	14	13	1.2 (0.7 to 2.1)
Ibuprofen	200	14	1808	19	19	0.9 (0.7 to 1.02)
Ibuprofen	400	40	4867	17	16	0.9 (0.8 to 1.04)
Ketoprofen	12.5	3	274	6	4	1.3 (0.5 to 3.6)
Ketoprofen	25	7	490	10	10	1.2 (0.7 to 2.0)
Ketoprofen	50	4	278	21	14	1.6 (0.9 to 2.6)
Ketoprofen	100	3	175	22	18	1.2 (0.7 to 2.2)
Lornoxicam	8	3	273	44	23	1.4 (0.9 to 2.2)
Lumiracoxib	400	3	460	13	18	0.7 (0.4 to 1.3)
Mefenamic acid	500	2	104	13	6	2.2 (0.7 to 7.2)
Naproxen	400/440	3	334	22	17	1.3 (0.8 to 2.2)
Naproxen	500/550	9	784	27	29	1.0 (0.7 to 1.2)
Rofecoxib	all doses	25	3688	34	35	1.0 (0.9 to 1.1)
Note that statistically significant results in risk ratio are in BOLD