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. 2019 Jan 10;4(1):e124002. doi: 10.1172/jci.insight.124002

Figure 6. Microstructural integrity (FA) in the parahippocampus regions correlates with serum DNRAb titers and performance on a spatial memory test in SLE subjects.

Figure 6

(A) Regression analysis of voxel-wise correlations between FA maps and serum DNRAb titers revealed a significant inverse correlation between FA values in the bilateral parahippocampal gyrus (BA 36/BA 20; yellow/red areas) and serum DNRAb titers. (B) Mean microstructural integrity in the bilateral parahippocampal gyrus exhibited a negative correlation with serum DNRAb titers (r = –0.64, P < 0.002, left). Mean microstructural integrity in the bilateral parahippocampal gyrus also exhibited a positive correlation with performance on a spatial memory test (r = 063, P < 0.002, right). Pearson’s product-moment correlation coefficient was used to evaluate the correlations between FA values and serum DNRAb titers and 2x2SMT scores.