Study	Reason for exclusion
Cady 2014	No single dose data (treatment over 3 months)
Edwards 2013	Study of cognitive function over 2 h. Did not assess pain, associated symptoms, or adverse events
Krymchantowski 2000	Enriched enrolment study investigating recurrence
Landy 2009	Post hoc analysis of Landy 2007 (secondary publication under Brandes 2007 Study 1; Brandes 2007 Study 2)
Smith 2007	Long‐term, open‐label study. Data pertains to quality of life and satisfaction outcomes only and not outcomes specified in this review
TRX107563	Probable migraine. Participants with migraine according to IHS criteria were excluded
White 2011	Long‐term study investigating effects of treatment on blood pressure. No single episode data for efficacy or adverse events
Winner 2007	Open‐label safety study

IHS: International Headache Society.