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. 2016 Apr 20;2016(4):CD008541. doi: 10.1002/14651858.CD008541.pub3
Summary of results: use of rescue medication
  Baseline pain Studies Attacks treated Treatment (%) Comparator (%) Risk ratio (95% CI) NNTp (95% CI)
Sumatriptan plus naproxen 85/500 mg vs placebo mild 8 3396 19 51 0.42 (0.38 to 0.47) 3.1 (2.8 to 3.4)
Sumatriptan plus naproxen 85/500 mg vs placebo ≥ mod 4 2169 28 59 0.47 (0.42 to 0.53) 3.2 (2.9 to 3.7)
Sumatriptan plus naproxen 50‐85/500 mg vs sumatriptan 50‐85 mg ≥ mod 3 1925 26 39 0.66 (0.58 to 0.76) 7.8 (5.9 to 11)
Sumatriptan plus naproxen 50‐85/500 mg vs naproxen 500 mg ≥ mod 3 1944 26 42 0.61 (0.54 to 0.70) 6.2 (4.9 to 8.3)
CI: confidence interval; NNTp: number needed to treat to prevent one event.