Summary of results: use of rescue medication | |||||||
Baseline pain | Studies | Attacks treated | Treatment (%) | Comparator (%) | Risk ratio (95% CI) | NNTp (95% CI) | |
Sumatriptan plus naproxen 85/500 mg vs placebo | mild | 8 | 3396 | 19 | 51 | 0.42 (0.38 to 0.47) | 3.1 (2.8 to 3.4) |
Sumatriptan plus naproxen 85/500 mg vs placebo | ≥ mod | 4 | 2169 | 28 | 59 | 0.47 (0.42 to 0.53) | 3.2 (2.9 to 3.7) |
Sumatriptan plus naproxen 50‐85/500 mg vs sumatriptan 50‐85 mg | ≥ mod | 3 | 1925 | 26 | 39 | 0.66 (0.58 to 0.76) | 7.8 (5.9 to 11) |
Sumatriptan plus naproxen 50‐85/500 mg vs naproxen 500 mg | ≥ mod | 3 | 1944 | 26 | 42 | 0.61 (0.54 to 0.70) | 6.2 (4.9 to 8.3) |
CI: confidence interval; NNTp: number needed to treat to prevent one event. |