Comparison 3. 5‐ASA vs control ‐ subgroups based on method of diagnosis.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Recurrence based on CT for initial diagnosis	7	1805	Risk Ratio (M‐H, Random, 95% CI)	0.69 [0.43, 1.09]
1.1 CT scan/ultrasound primary diagnosis	4	1391	Risk Ratio (M‐H, Random, 95% CI)	1.10 [0.89, 1.35]
1.2 Other	3	414	Risk Ratio (M‐H, Random, 95% CI)	0.30 [0.18, 0.50]
2 Recurrence based on CT scan for all events	7	1805	Risk Ratio (M‐H, Random, 95% CI)	0.69 [0.43, 1.09]
2.1 CT scan for primary diagnosis and recurrence	3	1274	Risk Ratio (M‐H, Random, 95% CI)	1.07 [0.81, 1.40]
2.2 Other	4	531	Risk Ratio (M‐H, Random, 95% CI)	0.45 [0.18, 1.09]