Drug and dose	Mean or median time to remedication (hours)		Percentage remedicating within 6 hours		Percentage remedicating within 8 hours
	Active	Placebo	Active	Placebo	Active	Placebo
Aspirin 600/650 mg	‐	‐	‐	‐	55	75
Aspirin 1000 mg	‐	‐	‐		67	83
Celecoxib 200 mg	6.6	2.6	‐	‐	‐	‐
Celecoxib 400 mg	8.4	1.6	‐	‐	‐	‐
Codeine 60 mg	2.7	2	38	46	‐	‐
Dexketoprofen 10/12.5 mg	‐	‐	54	74	‐	‐
Dexketoprofen 20/25 mg	‐	‐	52	75	‐	‐
Diclofenac fast acting 50 mg	7.6	3.8	‐	‐	33	71
Diclofenac fast acting 100 mg	‐	‐	‐	‐	50	78
Diclofenac potassium 25 mg	3.1	1.2	‐	‐	51	71
Diclofenac potassium 50 mg	4.5	1.7	‐	‐	59	69
Diclofenac potassium 100 mg	6.3	2	‐	‐	34	72
Diclofenac sodium 50 mg	‐	‐	‐	‐	59	69
Diflunisal 500 mg	9.8	3.2	22	66	‐	‐
Diflunisal 1000 mg	10.9	3.2	23	75	‐	‐
Etoricoxib 120 mg	20	2	50	92	‐	‐
Flurbiprofen 25 mg	‐	‐	35	70	‐	‐
Flurbiprofen 50 mg	‐	‐	25	66	‐	‐
Flurbiprofen 100 mg	‐	‐	16	68	‐	‐
Gabapentin 250 mg	2.4	2.1	69	86	‐	‐
Ibuprofen acid 200 mg	4.7	2.1	67	87	‐	‐
Ibuprofen acid 400 mg	5.6	1.9	43	80	‐	‐
Ibuprofen fast acting 200 mg	‐	‐	43	78	‐	‐
Ibuprofen fast acting 400 mg	‐	‐	32	82	‐	‐
Ibuprofen + caffeine 100/100 mg	‐	‐	‐	‐	34	66
Ibuprofen + caffeine 200/100 mg	‐	‐	‐	‐	26	60
Ibuprofen + paracetamol 200/500 mg	7.6	1.7	‐	‐	34	79
Ibuprofen + paracetamol 400/1000 mg	8.3	1.7	‐	‐	25	79
Ibuprofen + oxycodone 400/5 mg	> 6	2.2	40	83	‐	‐
Ketoprofen 12.5 mg	‐	‐	80	98	‐	‐
Ketoprofen 25 mg	‐	‐	46	79	‐	‐
Ketoprofen 50 mg	‐	‐	48	81	‐	‐
Ketoprofen 100 mg	‐	‐	43	85	‐	‐
Lornoxicam 8 mg	4.7	1.4	‐	‐	‐	‐
Naproxen 500/550 mg	8.9	2	‐	‐	‐	‐
Oxycodone 5 mg	2.3	2.1	‐	‐	‐	‐
Paracetamol 500 mg	‐	‐	35	63	‐	‐
Paracetamol 600/650 mg	3.5	2.4	52	65	‐	‐
Paracetamol 975/1000 mg	3.9	1.7	53	72	‐	‐
Paracetamol + codeine 300/30 mg	3.9	2.9	48	57	‐	‐
Paracetamol + codeine 600‐650/60 mg	4.1	2.4	59	80	‐	‐
Paracetamol + codeine 800‐1000/60 mg	5	2.3	‐	‐	‐	‐
Paracetamol + oxycodone 325/5 mg	4.3	2	66	85	‐	‐
Paracetamol + oxycodone 650/10 mg	9.8	1.5	55	83	‐	‐
Paracetamol + oxycodone 1000/10 mg	8.7	1.1	‐	‐	‐	‐
Rofecoxib 50 mg	13.8	1.9	‐	‐	27	74