Table 3. MHCI tetramer staining: TCR triplet clusters.
ligand | triplet fraction |
||
---|---|---|---|
wild-type | CD8-null | ||
3G | 0.993 | 0.984 | 3.7 ± 0.28 |
8Y | 0.921 | 0.733 | 22.6 ± 2.05 |
8T | 0.882 | 0.536 | 27.6 ± 6.71 |
wild-type: hla-a2; CD8-null: hla-a2 DT227/8KA
KD for the TCR/pMHCI interaction