Figure 2. Relative number of lymphocytes before and after radiation treatment.

Peripheral blood was obtained at day 0, 7, 16, 30, 40 and 99 and the number of lymphocytes was determined. Ionizing radiation (X-rays) was delivered at a dose of 3 Gy per daily fraction, at days 0-4 and 7-11. eMIP was administered at days 7-11 after each radiation treatment.

Group 1: The patients in this group, maintained lymphocyte levels around or above 1000 cells/μl before irradiation. No. 1. Ovarian cancer (endometroid adenocarcinoma) with lymph node metastasis. Radiation: delivered to the supraclavicular and the pelvic lymph nodes No. 2. Colon cancer (moderately differentiated tubular adenocarcinoma) with lung lymph node metastasis. Radiation: delivered to the pelvic and the superficial cervical lymph nodes. No. 3. Breast cancer (moderately differentiated tubular adenocarcinoma) with liver metastasis. Radiation: delivered to the liver left lobe S4. No. 4. Submandibular gland cancer (basal cell adenocarcinoma) with lung metastasis. Radiation: delivered to the left lung. No. 5. Colon cancer (high-differentiated adenocarcinoma) with liver metastasis. Radiation: delivered to the liver S4. No. 6. Sigmoid colon cancer with lymph node metastasis. Radiation: delivered to the supraclavicular and the pelvic lymph nodes. No. 7. Colon cancer (high differentiated adenocarcinoma) with lung metastasis. Radiation: derlivered to the right middle, the left lower and the upper lobes.

Group 2 (Inset): The patients in this group had lower numbers of lymphocytes even before irradiation (590-730 cells/μl). No. 8. Ovarian cancer (granulosa cell tumor) mesenteric recurrence. Radiation: delivered to the left iliopsoas muscle and the pelvis. No. 9. Oropharynx cancer (squamous cell carcinoma) with lung and cervical lymph node metastasis. Radiation: delivered to the left upper lobe. No. 10. Ovarian cancer dissemination (serous papillary cystic carcinoma). Radiation: delivered to the left pelvis and the rectal and the abdominal walls.