Organisational interventions compared to standard/usual care for prevention of medication errors
Patient or population: adults receiving medication in primary care Setting: primary care Intervention: organisational interventions (provision of pharmaceutical care, medication reviews, follow‐up visits by a healthcare professional (e.g. pharmacist, nurse or physician) Comparison: standard/usual care
Quality assessment							Effect	Quality	Importance
№ of participants/ studies	Study design	Risk of bias	Inconsistency	Indirectness	Imprecision	Other considerations	Relative/absolute (95% CI)
Number of hospital admissions
OI: 817/3100 (26.4%) SC: 850/3103 (27.4%) (11 studies)	Randomised trials	Seriousa	Seriousb	Not serious	Seriousc	None	Relative: RR 0.85 (0.71 to 1.03) Absolute: 41 fewer per 1000 (from 8 more to 79 fewer)	⊕⊝⊝⊝ Very low	Critical
Number of people admitted to hospital
OI: 2846/73,313 (3.9%) SC: 3221/78,924 (4.1%) (13 studies)	Randomised trials	Seriousa	Not serious	Not serious	Seriousc	None	Relative: RR 0.92 (0.86 to 0.99) Absolute: 0 fewer per 1000 (from 0 fewer to 6 fewer)	⊕⊕⊝⊝ Low	Important
Number of emergency departments visits
OI: 171/849 (20.1%) SC: 227/970 (23.4%) (5 studies)	Randomised trials	Serious a	Seriousb	Not serious	Seriousc	None	Relative: RR 0.75 (0.49 to 1.15) Absolute: 58 fewer per 1000 (from 35 more to 119 fewer)	⊕⊝⊝⊝ Very low	Critical
Mortality
OI: 3180/74,017 (4.3%) SC: 4085/80,945 (5.0%) (12 studies)	Randomised trials	Very seriousd	Not serious	Not serious	Seriousc	None	Relative: RR 0.94 (0.85 to 1.03) Absolute: 3 fewer per 1000 (from 2 more to 8 fewer)	⊕⊝⊝⊝ Very low	Important