Study	Reason for exclusion
Al‐Arifi 2014	Irrelevant intervention
Alassaad 2014	Not primary care
Alicic 2016	Protocol of a study
Barker 2012	This study does not appear to be a primary care intervention.
Barker 2016	Outcomes not relevant
Barnes 2014	Outcomes not relevant
Basheti 2016	Outcomes not relevant
Bell 2016	Not primary care
Benard‐Laribiere 2015	Irrelevant intervention
Bhatt 2014	Study protocol
Billington 2015	Outcomes not relevant
Bonnet‐Zamponi 2013	This was not a primary care intervention; it was done by geriatricians.
Briggs 2015	Not primary care
Carrington 2013	Irrelevant intervention
Clyne 2013	Outcomes not relevant
Clyne 2015	Outcomes not relevant
Clyne 2016	Outcomes not relevant
Cowper 1998	Cost‐effectiveness study that had data in a form not enabling data extraction.
Desveaux 2016	Study protocol
Dhalla 2014	Outcomes not relevant
Elliott 2014	Study protocol
Forster 2015	Study protocol
Fredericks 2013	Irrelevant intervention
Furniss 2000	Study was for a pre‐post design not included in the protocol
Geurts 2016	Outcomes not relevant
Gorgas 2012	This study did not occur in primary care.
Graffen 2004	Study was for a pre‐post design not included in the protocol
Guthrie 2016	Outcomes not relevant
Hallsworth 2016	Outcomes not relevant
Hanlon 1996	This study did not occur in primary care.
Hugtenburg 2009	This is not a randomised trial (it is described as a controlled intervention study and there is no evidence of randomisation).
Huiskes 2014	Outcomes not relevant
Keane 2014	Not primary care
Knowlton 1994	Not possible to extract appropriate data
Lee 1996	This study was not a randomised trial.
Leendertse 2011	This study was not a randomised trial.
Leendertse 2013	This study was not a randomised trial.
Liu 2010	This study was a conference abstract only and did not address adverse drug reactions.
Malin 2016	Outcomes not relevant
Mills 2001	This study is reported elsewhere (see Furniss 2000, also excluded)
Montero‐Balosa 2016	Not a randomised trial
Moreno 2016	Not a randomised trial
Naunton 2003	This is a hospital intervention and not done in primary care. It appears that the study pharmacist is recruited from the hospital. As it says, the pharmacist complied with the Society of Hospital Pharmacist clinical pharmacy services. It is also published in a hospital journal.
Neven 2016	Not primary care
Ni 2016	Not a randomised trial
Perula 2014	Outcomes not relevant
Phung 2013	Study protocol
Pinnock 2013	Irrelevant intervention
Przytula 2015	Study protocol
Safran 1993	This study was not a randomised trial
Saltzberg 2011	This study was not a randomised trial
Setter 2009	The outcomes reported are not appropriate for this study
Sinnott 2015	Outcomes not relevant
Stingl 2016	Study protocol
Sturgess 2003	Reported elsewhere (see Bernsten 2001)
Wolf 2015	Outcomes not relevant
Wooster 2016	Study protocol
Xin 2014	Not primary care
Yuan 2003	Complex study, which made data extraction not possible.