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. 2019 Apr 26;14(4):e0215737. doi: 10.1371/journal.pone.0215737

Table 3. Diagnostic performance of fetal biometric parameters for the prediction of small for gestational age according to the gestational age ranges.

Gestational age (weeks) AUC (95% CI) Sensitivity (%) Specificity (%) PPV (%) NPV (%)
BPD 24+0–28+6 0.727 (0.664–0.786) 82.1 55.8 35.0 91.5
29+0–32+6 0.701 (0.64–0.764) 76.8 58.3 36.7 88.8
33+0–35+6 0.708 (0.647–0.762) 44.2 86.4 52.3 82.2
HC 24+0–28+6 0.697 (0.631–0.753) 80.8 50.2 32.0 90.0
29+0–32+6 0.681 (0.613–0.741) 62.6 68.8 38.8 85.4
33+0–35+6 0.675 (0.61–0.732) 49.0 76.7 41.5 81.7
AC 24+0–28+6 0.806 (0.756–0.856) 79.5 71.7 44.9 92.3
29+0–32+6 0.804 (0.75–0.851) 79.8 69.4 45.1 91.6
33+0–35+6 0.805 (0.756–0.848) 64.4 83.5 56.8 87.5
FL 24+0–28+6 0.651 (0.585–0.712) 74.4 53.9 31.9 87.9
29+0–32+6 0.683 (0.624–0.745) 79.8 52.2 34.5 89.1
33+0–35+6 0.687 (0.63–0.743) 49.0 77.0 41.8 81.8
EFW 24+0–28+6 0.775 (0.718–0.828) 74.4 70.3 42.0 90.4
29+0–32+6 0.807 (0.754–0.854) 74.7 73.9 47.4 90.3
33+0–35+6 0.826 (0.778–0.872) 60.6 87.6 61.2 86.8

AUC, area under the curve; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; BPD, biparietal diameter; HC, head circumference; AC, abdominal circumference; FL, femur length; EBW, estimated fetal weight