Table 4. The magnitude (maximum diurnal changes [ΔMax.]) of diurnal variation of retinal vessel density and hemodynamic parameters between healthy subjects and POAG.
| Healthy subjects (N = 19) |
POAG (N = 20) |
P-valuea | |
|---|---|---|---|
| ΔMax.in peripapillary RVD (%) | |||
| Average | 5.73±3.85 | 9.71±7.04 | 0.013 |
| Disc head | 6.32±3.74 | 13.02±9.18 | 0.005 |
| pSuperior | 5.01±2.59 | 8.30±4.16 | 0.006 |
| pInferior | 5.18±4.77 | 8.07±5.61 | 0.091 |
| pTemporal | 5.96±4.36 | 8.59±4.85 | 0.084 |
| pNasal | 6.19±3.81 | 10.55±11.40 | 0.119 |
| ΔMax.in macular RVD (%) | |||
| Average | 5.51±3.45 | 7.22±4.73 | 0.042 |
| Fovea | 5.10±3.90 | 4.37±3.87 | 0.559 |
| mSuperior | 5.71±3.73 | 7.94±3.77 | 0.051 |
| mInferior | 5.98±3.18 | 8.92±4.95 | 0.034 |
| mTemporal | 5.66±3.15 | 6.72±6.77 | 0.540 |
| mNasal | 5.28±3.28 | 7.13±4.28 | 0.139 |
| ΔMax.in hemodynamics (mmHg) | |||
| SBP | 17.26±9.45 | 22.25±8.34 | 0.089 |
| DBP | 14.73±8.94 | 21.40±7.10 | 0.014 |
| IOP | 2.84±1.01 | 3.95±1.19 | 0.003 |
| MOPP | 9.80±5.70 | 13.41±4.84 | 0.039 |
aIndependent t-test, bolded values represent significant, P< 0.05
RVD, retinal vessel density; SBP, systolic blood pressure; DBP, diastolic blood pressure; IOP, intraocular pressure; MOPP, mean ocular perfusion pressure.