Table 1.

Comparisons between Dox and control cohorts via Mann-Whitney U test

	Dox (n = 6)	Control (n = 5)	U	P
Hydroxyproline, µmol/right lung	3.67 (3.48, 3.77)	1.24 (1.20, 1.25)	0	0.004*
Airway resistance, cmH2O·s/ml	0.82 (0.71, 1.00)	0.50 (0.48, 0.56)	2	0.02*
Airway elastance, cmH2O/ml	57.81 (48.45, 70.90)	27.02 (25.50, 27.71)	1	0.009*
Compliance, ml/cmH2O·kg	0.018 (0.014, 0.021)	0.037 (0.036, 0.039)	1	0.009*
Pleural thickness, µm	73.77 (54.26, 91.77)	7.04 (6.54, 7.38)	0	0.004*
High-density lung volume percentage, %	35.25 (24.41, 48.38)	5.16 (5.06, 5.28)	0	0.004*
Tidal volume, ml	0.091 (0.078, 0.094)	0.322 (0.247, 0.322)	30	0.004*
Respiratory rate, breaths/min	74.07 (65.60, 86.43)	70.80 (69.46, 93.63)	15	1
Minute ventilation, ml/min	6.78 (5.49, 7.85)	23.15 (22.34, 23.88)	30	0.004*
Body mass, g	23.95 (23.30, 25.95)	23.30 (23.00, 26.70)	14	0.93

All quantities are displayed as median (1st quartile, 3rd quartile).

^*Statistically significant.