NCT01172405.

Methods	Randomised, double‐blind, placebo‐controlled, parallel‐group study Probably single dose
Participants	Headache (migraine or tension). Pain intensity mild to moderate, 2 to 5 headache attacks in previous 30 days Estimated N = 144 Age 18 to 65 years M and F
Interventions	Ibuprofen 400 mg + caffeine 200 mg Ibuprofen 400 mg 1 or 2 tablets when presenting headache (sic)
Outcomes	Intensity of headache before and after initiation of treatment, using Functional Disabling Scale Tolerability ‐ assessed by investigator
Notes	Unclear if completed; estimated final collection date for primary outcome October 2012 Email to Claudia Domingues (contact person) on 28 August 2014 bounced: "address failed" Sponsor: Mantecorp Industria Quimica e Farmaceutica Ltd.